Successful use of the catheter has been reported at Privatklinik Proebstle in Mannheim, Germany and three medical centres in The Netherlands (Antonius Hospital in Nieuwegein, Rijnstate Hospital in Arnhem, and Maastricht University Medical Centre).
ClariVein is a non-thermal approach that uses a mechanical rotating dispersion wire to mix and disperse a sclerosant on the vessel wall to cause ablation of a vein.
This technique has several advantages; unlike radiofrequency and laser therapy, ClariVein does not require tumescent anaesthesia, and can be used to treat near nerve bundles without concern for nerve damage, so the procedure is fast and essentially pain-free. The catheter is also fully disposable and a generator is not required, so the costs of operation and maintenance are eliminated.